What is PXE?
Pseudoxanthoma elasticum, PXE, is an inherited disorder that causes select elastic tissue in the body to become mineralized, that is, calcium and other minerals are deposited in the tissue. This can result in changes in the skin, eyes, cardiovascular system and gastrointestinal system.
The most common result is hemorrhages in the eye with potential sight-threatening scarring, which typically starts in mid-life of a person affected by PXE.
What is PXE International?
PXE International seeks to help those affected by PXE to continue to live happy, healthy, productive lives. This non-profit organization is doing everything possible to find a treatment for this disease.
Is my donation tax deductible?
Yes, PXE International is a 501(c)(3) non-profit organization. You will receive a receipt for your donation that can be used for your end-of-year taxes.
Where does my money go?
PXE International not only supports patients and their loved ones by providing information and education, we also facilitate medical research in an international community of incredible and dedicated scientific labs. Through our tireless efforts to advance the research into pseudoxanthoma elasticum, we increase understanding of this disorder and improve the process itself. Every dollar donated is critical to the success of our research into the causes and treatment of PXE.
Your donation helps us continue in our mission to initiate, fund and conduct research; provide support for individuals and families affected by pseudo-xanthoma elasticum; and provide resources for healthcare professionals.


