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Emily Chew, MD, PhD

Emily Chew

Deputy Director of the Division of Epidemiology and Clinical Applications (DECA)
National Eye Institute, National Institutes of Health
Bethesda, Maryland

Emily Chew, MD, PhD, is the Deputy Director of the Division of Epidemiology and Clinical Applications (DECA), at the National Eye Institute, the National Institutes of Health in Bethesda, Maryland. She is also the Chief of the Clinical Trials Branch in the division.  Emily received her medical degree and her ophthalmology training at the U. of Toronto, Canada.  She completed her fellowship in medical retina at the Wilmer Eye Institute, the Johns Hopkins Medical Institutes and the U. of Nijmegen, the Netherlands. 

Her research interest includes phase I/II clinical trials and epidemiologic studies in retinovascular diseases such as age-related macular degeneration, diabetic retinopathy, and other ocular diseases.  She has worked extensively in large multi-centered trials headed by the staff from her division, including the Early Treatment Diabetic Retinopathy Study (ETDRS), the Age-Related Eye Disease Study (AREDS) and the Age-Related Eye Disease Study 2 (AREDS2), which she chairs.  She works on other clinical trials in collaboration with other institutes within NIH.
 

Areas of Interest

Diseases of the Macula, Genetic Conditions, Principle Investigator for Age-Related Macular Degeneration Eye Disease Study (AREDS)
 

Publications


Klein ML, Ferris FL 3rd, Francis PJ, Lindblad AS, Chew EY, Hamon SC, Ott J. Progression of Geographic Atrophy and Genotype in Age-Related Macular Degeneration. Ophthalmology. 2010 Aug;117(8):1554-9.e.1. Free article in PubMed.

Krishnadev N, Meleth AD, Chew EY. Nutritional supplements for age-related macular degeneration. Curr Opin Ophthalmol. 2010 May;21(3):184-9. Free article in PubMed.

Lee TK, Forooghian F, Cukras C, Wong WT, Chew EY, Meyerle CB. Complementary angiographic and autofluorescence findings in pseudoxanthoma elasticum. Int Ophthalmol. 2010 Feb;30(1):77–9. Free article in PubMed.

Lindblad AS, Lloyd PC, Clemons TC, Gensler GR, Ferris FL 3rd, Klein ML, Armstrong JR. Age-Related Eye Disease Study Research Group. Change in area of geographic atrophy in the Age-Related Eye Disease Study: AREDS report number 26. Arch Ophthalmol. 2009;127:1168-74.

SanGiovanni JP, Argon E, Meleth AD, Reed GF, Sperduto RD, Clemons TE, Chew EY. Omega-3 long-chain polyunsaturated fatty acid intake and 12-year incidence of neovascular age-related macular degeneration and central geographic atrophy: a prospective cohort study from the Age-Related Eye Disease Study. Am J Clin Nutr. 2009 Dec;90(6):1601-7.

Forooghian F, Cukras, C, Meyerle, Chew EY, Wong WT. Tachyphylaxis following intravitreal bevacizumab for exudative age-related macular degeneration. Retina. 2009 Jun;29(6):723-31. Free article in PubMed.

SanGiovanni JP, Chew EY, Agron E, Clemons TE, Ferris FL, Gensler G, Linblad AS, Milton RC, Seddon JM, Klein R, Sperduto RD for the Age-Related Eye Disease Study Research Group. The Relationship of Dietary Lipid Intake with Incident Age-Related Macular Degeneration: AREDS Report Number 23. Arch of Ophthalmol. 2008 Sep;126(9):1274-79. Free article in PubMed.

Huang LL, Coleman HR, Kim J, de Monasterior F, Wong WT, Schleicher RL, Ferris FL. Chew EY. Oral supplementation of lutein/zeaxanthin and omega-3 long chain polyunsaturated fatty acids in persons aged 60 years and older, with and without age-related macular degeneration. Invest Ophthalmol Vis Sci. 2008 Sep;49(9):3864-9.

Klein M, Ferris Fl, Chew EY, and the Age-Related Eye Disease Study Research Group. Retinal Precursors and the Development of Geographic Atrophy in Age-Related Macular Degeneration. Ophthalmol. 2008 Jun;115(6):1026-31.

SanGiovanni JP, Chew EY, Clemons TE, Ferris FL 3rd, Gensler G, Lindblad AS, Milton RC, Seddon JM, Sperduto RD and the Age-Related Eye Disease Study Research Group. The Relationship of Dietary Carotenoids, Vitamin E, and Vitamin C with Age-related Macular Degeneration: A Case-Control Study in the Age-Related Eye Disease Study. AREDS Report Number 22. Archives of Ophthalmology. 2007 Sep;125(9):1225-32.

Connor KM, SanGiovanni JP, Lofqvist C, Aderman CM, Chen J, Higuchi A, Hong S, Pravda EA, Majchrzak S. Carper D, Hellstrom A, Kang JX, Chew EY, Salem NN, Serhan CN, Smith LEH. Increased dietary intake of ω-3 PUFA reduces pathological retinal angiogenesis. Nat Med. 2007 Jul:13(7):868-73.

Coleman H, Chew E*. Nutritional supplementation in age-related macular degeneration. Curr Opin Ophtahlmol. 2007;18(3):220-3.

Rosenthal J, Kim J, deMonasterio F, Thompson DJS, Bone RA, Landrum JT, Moura F, Khachik F, Chen H, Schleicher RL, Ferris FL, Chew EY*. Dose ranging study of lutein supplementation in persons aged 60 years or older. Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5227-33.

Khachik F, de Moura FF, Chew EY, Douglass LW, Ferris FL 3rd, Kim J, Thompson DJ. The effect lutein and zeaxanthin supplementation on metabolites of these carotenoids in the serum of persons aged 60 or older. Invest Ophthalmol Vis Sci. 2006;47:5234-42.

Chew EY, Clemons T. Vitamin E and the age-related eye disease study supplementation for age-related macular degeneration. Arch Ophthalmol. 2005 Mar;123(3):395-6.

SanGiovanni JP. Chew EY. The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Progress in Retinal and Eye Research. 2005;24:87-138.

Chew EY, SanGiovanni JP. Lutein. 2005 Encyclopedia of Dietary Supplements, pp. 409 – 420, Marcel Dekker, Inc.

The Age-Related Eye Disease Study Group. Impact of antioxidants, zinc, and copper on cognition in the elderly. A randomized, controlled trial. AREDS Report No. 12. Neurology. 2004 Nov;63(9):1705-07. Free article in PubMed.

The Age-Related Eye Disease Study Research Group. The effect of five-year zinc supplementation on serum zinc, serum cholesterol and hematocrit in persons randomly assigned to treatment group in the Age-Related Eye Disease: AREDS Report No. 7. J. Nutr. 2002 Apr;32(4):697-702. Free article in PubMed.

The Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss. AREDS Report No. 9. Arch Ophthalmol. 2001 Oct;119(10):1439-52. Free article in PubMed.

The Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss. AREDS Report No. 8. Arch Ophthalmol. 2001 Oct;119(10):1417-36. Free article in PubMed.

The Age-Related Eye Disease Study Research Group. A clinical trial of zinc and antioxidants. The Age-Related Eye Disease Report No. 2. J Nutr. 2000 May;130(5S Suppl):1516S-9S. Free article in PubMed.

 

Last modified: 03/08/2013