Karobi Moitra, MS, PhD

Karobi Moitra, MS, PhD
Clare Boothe Luce Assistant Professor of Molecular Biology
Trinity Washington University, Washington, DC

Dr. Moitra received her Ph.D in zoology in 1999 from the University of Burdwan in India and was an Assistant Professor of Zoology at Ramananda College in India. She relocated to the United States and trained in biochemistry and molecular biology at the Uniformed Services University of the Health Sciences in Bethesda, MD and at the National Cancer Institute at Frederick, MD. She has received the Fellows Award for Research Excellence from the NIH for her research centered around the role of ABC transporters in human disease and drug resistance. Dr. Moitra is currently an Assistant Professor of Molecular Biology at Trinity Washington University in Washington, DC. She is also dedicated to educational outreach and in training and mentoring students. She enjoys writing fiction based on science and has contributed her writing to the Human Genre Project. Outside of the laboratory she enjoys reading, cooking, traveling and has recently started a new hobby, creating artwork based on her science.

Read an interview with Karobi from November 2011.
 

Areas of Interest

Genetics of PXE

Publications

Moitra K, Scally M, McGee K, Lancaster G, Gold B and Dean M. Molecular evolutionary analysis of ABCB5: The ancestral gene is a full transporter with potentially deleterious single nucleotide polymorphisms. PLoS One. 2011 Jan 27;6(1):e16318.

Fukuda Y, Aguilar-Bryan L,Vaxillaire M, Dechaume A, Wang Y, Dean M, Moitra K, Bryan J and Schuez JD. Conserved intramolecular disulphide bond is critical to the trafficking and fate of ATP binding cassette (ABC) transporters ABCB6 and sulphonyl urea receptor. J Biol Chem. 2011 Mar 11;286(10):8481-92.

 

Review Articles

Silverton L, Dean M and Moitra K. Variation and Evolution of the ABC Transporter Genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: Implication for Pharmacogenetics and Disease. Drug Metab Drug Interact. 2011;26(4):169–179.

Moitra K, Silverton L, Limpert K, Im K and Dean M. Moving out: From sterol transport to drug resistance – the ABCG subfamily of efflux pumps. Drug Metab Drug Interact. 2011;26(3):105-111.

Moitra K, Lou H and Dean M. Multidrug Efflux Pumps and Cancer Stem Cells: Insights into Multidrug Resistance and Therapeutic Development. Clin Pharmacol Ther. 2011 Apr;89(4):491-502.

Moitra K and Dean M. Evolution of ABC transporters by gene duplication and their role in human disease. Biol Chem. 2011 Jan;392(1-2): 29-37.